A GO circle plot is a type of visualization chart used to display the results of Gene Ontology (GO) enrichment analysis. It typically consists of multiple concentric circles (tracks), with each circle layer representing different information.

Input

The first column is "gene", the second column is "logFC value", and they are separated by a tab character (\t).

Output

Chart Description

1. GO Chord Diagram

Structure:

• The GO chord diagram is based on a circular layout.

• One side of the outer ring represents significantly enriched GO terms (e.g., BP, CC, MF), while the opposite side displays the input genes.

Connections (Chords):

• Each chord connects a GO term to a gene, indicating that the gene is annotated/enriched in that GO term.

• These connections visually reveal which genes participate in which functional processes and whether different GO terms share common genes.

Colors & Labels:

• Different GO terms and genes are distinguished by unique colors.

2. GO Cluster Diagram

Structure:

• The cluster diagram groups GO terms based on functional similarity or gene overlap, illustrating relationships and similarities between GO terms.

Purpose:

• Helps identify functionally related GO terms or those with significant gene overlap.

• Aids in understanding the overall structure of biological processes.